Dear Parent/Guardian or Health Adviser,
Kre-Alkalyn + Vit E is a product based on superior forms of natural ingredients.
This product is not recommended for children younger than 16 years old.
Q. What is better than Kre-Alkalyn®?
A. Kre-Alkalyn® + Vitamin E
Why? It stays with you longer.
A World First from Powerband!
Discover the next new level in creatine supplementation.
Kre-Alkalyn® gets even better
when combined with a high quality source of Vitamin E.
A long time before creatine was ever used by athletes and body builders, scientists back in 1962 set out to measure the direct relationship with of Vitamin E and creatine stored in muscle. In the summary of their research published in a reputable peer reviewed journal, they summarized that when Group A’s diet was set up to make the subjects deficient in Vitamin E, they observed a significant reduction in muscle creatine stores and higher levels of creatine being passed in their urine. Group B whose levels of Vitamin E were kept at the constant pre-study levels exhibited no significant change in creatine levels stored in muscle. Group C whose vitamin E levels in their diet were increased exhibited a measurable net increase in creatine levels in their muscle tissue. The relationship appears to be the ability of the muscle cells to hold the creatine for longer thus leading to the ability of the body to store more optimum total creatine pools.
This study is well known to serious researchers on creatine but because it was not published in the digital age and some 30 years before any commercial production and sale of creatine, it is unfortunately a study which the supplement industry has failed to find out…. until now. A world first! We are the first company to bring this important breakthrough formula to the world market.
Important details for those that want to know more:
Why Kre-Alkalyn® + Vitamin E?
Firstly, Why Kre-Alkalyn® (creatine)?
Kre-Alkalyn® (Creatine) is a nitrogenous organic acid. Approximately 95% of the Creatine in the body is located in skeletal muscle cells. These cells can store more Creatine than what you normally get from your daily diet and/or is synthesized by the body. By supplementing your diet with Kre-Alkalyn®, your muscles can retain more Creatine. Kre-Alkalyn® helps (as a carrier) to supply energy to all cells, primarily muscle, by readily supplying macroergic bonds (known as the Phosphocreatine shuttle). These bonds contain energy needed for the replenishment of the ATP pool (Adenosine TriPhosphate).
There is common ignorance in the supplement industry that ATP directly causes muscle contraction (like an engine). In fact it is the opposite. The relaxed muscle fiber represents a loaded spring. When it unloads to the trigger of a nervous impulse this does not require energy. ATP in fact is needed for muscle relaxation, which can be compared to the loading a spring. Without it there is rigor mortise (like when the body goes stiff when someone dies). It requires energy to open or expand the spring back out again ready to be released again.
Creatinephosphate, which the body sources from Kre-Alkalyn®, acts as cell energy reserve needed for muscle contraction. Creatine in a 3 g daily dose is scientifically proven to increase performance in successive burst of short-term, high intensity exercise like weight training and interval cardio*.
Aerobic verses Anaerobic
Aerobic (when there is plenty of oxygen) is much cleaner as a mechanism for burning energy and making it into ATP. When oxygen is insufficient the Anaerobic mode kicks in which is less efficient and leads to toxic metabolites (lactic acid).
By supplementing your body with Kre-Alkalyn® you delay the need for Anaerobic based production of energy. Therefore you minimize the negative effects from Anaerobic metabolism including recovery rate yet keeping all the positives, including muscle hypertrophy and increased cardiovascular endurance simply because when there is less lactate in your body and your blood stream, it is less work for your heart, lungs and kidneys.
Why Kre-Alkalyn® + Vitamin E?
Deficiencies cause mal-absorption. For maximum absorption of creatine we have combined it with Vitamin E. A study1 into creatine metabolism found deficiencies in Vitamin E resulted in lower muscle creatine levels and higher levels of creatinurea (creatine being excreted by the subjects urine). Three groups were studied – Deficient in Vit E, Control and Supplemented with Vit E. In this study the group that were supplemented with Vitamin E showed a greater level of creatine in the muscle than the control group.
Writing in the journal Free Radical Biology and Medicine2, researchers have shown that vitamin E is essential in the repair of the plasma membranes of cells – meaning that without an adequate an adequate supply of vitamin E cells cannot repair properly after damage. That could be a big problem for many cells, such as muscle cells, which get membrane tears just from being used, said the researchers behind the study – led by Dr Paul L. McNeil at the Medical College of Georgia at Georgia Regents University. "Every cell in your body has a plasma membrane, and every membrane can be torn," said McNeil – who noted that muscle cells are constantly torn simply through being used or trained. Trainers are constantly exerting near maximal effort using their muscle to force adaptation. "This means, for the first time, 83 years after its initial discovery, we know what the cellular function of vitamin E is. Part of how we build muscle is a more natural tearing and repair process - that is the no pain, no gain portion - but if that repair doesn't occur, what you get is muscle cell death. If that occurs over a long period of time, what you get is muscle-wasting disease. " said McNeil.
In the US research is indicating adult on average eat approximately half the US Dietary Reference Intake (DRI) for vitamin E—7.5 mg of the recommended 15 mg per day. Vitamin E is one of the most common vitamin deficiencies in the United States, with as many as 92% of men and 98% of women failing to reach target intake goals. In 2006, a research group from Tufts University3 did a statistical model of the best way to ensure vitamin E nutrition while staying within normal calorie levels and without impairing other nutrient intake. Among their conclusions, they asserted that a low intake of nuts and seeds—70% of their subjects didn't eat any of either—was predictive of low vitamin E intake. Analyzing this conclusion in reverse, this is further evidence that nuts and seeds can be a good place to start when trying to achieve strong vitamin E nutrition. (Of course, low intake of dark green leafy vegetables by the average U.S. adult is another reason why so many people in the U.S. fail to meet their vitamin E needs.4)
Why use the most expensive form D-Alpha-Tocophoryl?
There are synthetic (DL-apha-Toc…..) and natural forms (D-alpha-Toc….) of Tocopherol. On supplement labels, natural vitamin E is listed as d-alpha tocopherol, d-alpha tocopheryl acetate, or d-alpha tocopheryl succinate. In contrast, the synthetic forms of vitamin E are labeled as dl- forms. While synthetic forms of other vitamins appears to be of little difference to absorption and utilization of vitamins, there is a lot of concern about the synthetic form of Vitamin E (the DL-alpha form) as being not equally effective. Alpha-tocopherol is the most biologically active form of vitamin E. Its natural form consists of one isomer. In contrast, synthetic alpha-tocopherol contains eight different isomers, of which only one (which consists of approximately 12% of the synthetic molecule) is identical to natural vitamin E. The other seven isomers range in potency from 21 percent to 90 percent of the natural form of d-alpha-tocopherol. Most companies on the market only sell the DL form because it cheaper to buy.
It is key to understand how the body absorbs natural and synthetic supplements differently. How the body uses vitamin E is determined by its molecular structure. Researchers have found that natural vitamin E is assimilated far more than synthetic versions.
Specific binding and transport proteins produced in the liver select the natural d-alpha form of vitamin E and ignore almost all other forms. In one experiment, Japanese researchers put seven healthy young women alternately on natural and synthetic vitamin E to. It took 300 mg synthetic vitamin E to equal the blood levels achieved by a 100-mg dose of natural vitamin E5.
In a study at East Tennessee State University, Johnson City, researchers gave a variety of subjects alternatively 30 mg/day or 300 mg/day vitamin E. Each supplement contained half-natural and half-synthetic vitamin E. Both forms were chemically labeled to distinguish them from other vitamin sources. In the blood stream the concentration of natural vitamin E increased two times more than the synthetic form in healthy subjects and pregnant women. In umbilical cords, natural vitamin E levels were three times higher than synthetic vitamin levels. Vitamin E transits through the blood stream on its way to the tissues. The researchers tracked short-term tissue assimilation of natural and synthetic vitamin E in study volunteers prior to elective surgery. Tissue absorbs nutrients over a much longer period of time, compared to the blood stream. After seven to 23 days of administration, natural vitamin E levels became higher than synthetic levels.6
Researchers conducted long-term tissue assimilation studies on two cancer patients. One patient took 30 mg/day half natural, half synthetic vitamin E for one year, and the other took 300 mg/day for almost two years. In both patients, blood and tissue levels of natural vitamin E rose twice as high as the synthetic.7
Researchers at Oregon State University, Corvallis, found the human body excretes synthetic vitamin E three times faster than the natural form.8
Recovery is the foundation of maintaining health. To perform at your peak be it with lifting heavy weights, or training for sprinting or endurance type events, your muscles need to have recovered with reloading your ATP stores, phosphocreatine pool, glycogen stores, lactate levels and raw materials such as amino acids, fats, cholesterol for more hormones to be made. Recovery is what puts you into anabolic drive.
Sleep is the only time when growth hormone is produced and is the key time for recovery by the body. So proper consistent sleep patterns is also critical for aiding in recovery.
Caution: Vitamin E is a fat soluable vitamin which means that it can build up in the body to dangerous levels if too much is taken ongoing. It is important to understand that “taking more” does not lead to even more superior results. We have used a high quality source and combined it with Kre-Alkalyn® in levels which we believe gives the best value and results in a timed delivery.
*This statement has been scientifically proven and authorized by the European Food Safety Authority.
1. G. B. GERBER, G. GERBER, T. R. KOSZALKA, AND V. M. EMMEL. Division of Experimental Radiology and Departments of Biochemistry and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York. “Creatine metabolism in vitamin E deficiency in the rat”
2. Free Radical Biology and Medicine. Volume 84 , July 2015, Pages 246–253, doi: 10.1016/j.freeradbiomed.2015.03.016 "The antioxidant requirement for plasma membrane repair in skeletal muscle" Authors: Mohamed Labazi, et al
3. Gao X, Wilde PE, Lichtenstein AH, et al. The maximal amount of dietary alpha-tocopherol intake in US adults (NHANES 2001-2). J Nutr 2006;136:1021-6.
4. U.S. Department of Agriculture, Agricultural Research Service. 2012. Total Nutrient Intakes: Percent Reporting and Mean Amounts of Selected Vitamins and Minerals from Food and Dietary Supplements, by Family Income and Age, What We Eat in America, NHANES 2009-2010.
5. Kiyose C, et al. Biodiscrimination of alpha-tocopherol stereoisomers in humans after oral administration. Am J Clin Nutr 1997 (Mar); 65 (3): 785-9
6. Burton GW, et al. Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E Am J Clin Nutr 1998; 67: 669-84
8. Traber MG, et al.. Synthetic as compared with natural vitamin E is preferentially excreted as a-CEHC in human urine: studies using deuterated a- tocopheryl acetate. FEBS Letters 1998 (Oct 16); 437: 145-8